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KMID : 0357919730070020127
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Korean Journal of Pathology
1973 Volume.7 No. 2 p.127 ~ p.137
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Alveolar Cell Carcinoma of the Lung -An Electron Microscopic Study-
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¾È±àȯ(äÌÐæüº)
¿©ÀçÀ±(åþî¤ëÊ)/À¯¿øÇÏ(׳êªù¾)/±è¼±È£(ÐÝà¼ûÄ)/°©ÇöÇÊ(Ë£úèù°)/¹Ú»ó¹«(ÚÓßÂ)/±èÁ¤±æ(ÐÝïÙÑÎ)/±èÁ¤¼÷(ÑÑïöâ×)/¹ÚÂùÀÏ(ÚÓóÇìé)
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Abstract
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Alveolar cell carcinoma constitutes only 1 to 8% of all primary lung malignancies but
it has occasioned considerable controversy about its histogenesis, morphology and
prognostic implication.
Authors experienced recently a case of alveolar cell carcinoma of the lung occurring
in a 64-year-old male. He was admitted for the evaluation of coughing and
expectoration of sputum for 3 months. X-ray film of chest showed diffuse radio-opacity
of the left lower lobe of lung. Bronchoscopy was unrevealing. Exploratory thoracotomy
and left lower lobectomy was performed to show diffuse consolidation involving entire
left lower lobe of the lung.
Grossly, cut surface exhibited diffusely yellow white or pale grayish firm lobar
consolidation, which resembled lobar pneumonia in the stage of gray hepatization or
lipoid pneumonia.
Microscopically, proliferating columnar epithelia were supported by thin or slightly
thickened alveolar septa, presenting an alveolar pattern of growth.
Electron microscopically, the tumor cells lining the alveolar basement membrane had
ultrastructural features resembling pneumonocyte type B. It was concluded that the
tumor cells in this alveolar cell carcinoma were derived from pneumonocyte type B.
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